Lead Exposure & Fevers During Pregnancy Can Lead to Autism

Autism is a complex neurodevelopmental disorder that affects communication, social interaction, and behavior. There is still much to learn about the causes of autism, but recent studies have suggested that lead exposure and maternal fever during pregnancy may be contributing factors.

reuben kesherim
Ruben Kesherim
July 8, 2023

Lead Exposure & Fevers During Pregnancy Can Lead to Autism

Lead Exposure and Autism

Lead is a toxic metal that can cause serious health problems, especially in children. Exposure to lead can lead to developmental delays, learning difficulties, and behavioral problems. Studies have also linked lead exposure to an increased risk of autism.

A study published in JAMA Pediatrics in 2017 found that children who were exposed to lead during pregnancy and early childhood were more likely to be diagnosed with autism.

lead exposure and autism

The study followed 553 children from birth to age 14 and found that those with higher levels of lead in their blood were more likely to have autism.

Lead exposure during pregnancy can also affect the developing brain and nervous system of the fetus. This can lead to lifelong cognitive and behavioral problems, including autism.

Maternal Fever and Autism

Maternal fever during pregnancy has also been linked to an increased risk of autism. A study published in Molecular Psychiatry in 2019 found that children born to mothers who had a fever during pregnancy were more likely to develop autism.

The study looked at data from over 95,000 children in Denmark and found that those born to mothers who had a fever during pregnancy had a 34% increased risk of autism. The risk was even higher if the fever occurred during the second trimester of pregnancy.

Fever is a sign that the body is fighting an infection, but it can also trigger an inflammatory response in the body. This inflammation can affect the developing brain of the fetus and increase the risk of autism.

Preventing Lead Exposure and Maternal Fever

Preventing lead exposure and maternal fever during pregnancy is important for the health and well-being of both the mother and the baby. Here are some tips to help prevent lead exposure and maternal fever:

Lead Exposure Prevention:

  • Test your home for lead.
  • Use lead-free paint.
  • Avoid using traditional home remedies that may contain lead.
  • Wash hands and toys frequently.
  • Feed your child a healthy diet rich in calcium, iron, and vitamin C.

Maternal Fever Prevention:

  • Get vaccinated before pregnancy.
  • Avoid contact with sick people.
  • Practice good hygiene, such as washing hands frequently.
  • Take acetaminophen (Tylenol) to reduce fever if necessary.

The Science Behind Why Lead Exposure Causes Autism

Lead is a toxic metal that can damage the brain and nervous system. When lead enters the body, it can interfere with the normal functioning of neurons and disrupt the formation of synapses. This can lead to cognitive and behavioral problems, including autism.

Research suggests that lead exposure during pregnancy may be particularly harmful to the developing brain of the fetus. The developing brain is highly susceptible to environmental toxins, including lead.

Lead exposure during this critical period of development can alter gene expression, disrupt neural pathways, and affect neurodevelopmental processes.

Studies have also shown that lead exposure can cause oxidative stress in the body, which can damage cells and tissues. Oxidative stress has been linked to a number of health problems, including neurological disorders like autism.

In addition to direct effects on the brain, lead exposure may also contribute to autism by disrupting immune function. Lead exposure has been shown to impair immune function in both children and adults. This impairment may make individuals more vulnerable to infections and other environmental insults that could increase their risk of developing autism.

Overall, there is strong evidence linking lead exposure during pregnancy and early childhood to an increased risk of autism. While much work remains to be done in understanding the complex causes of this disorder, reducing exposure to environmental toxins like lead is an important step in protecting children's health and well-being.

FAQs

What is lead?

Lead is a toxic metal that can cause serious health problems, especially in children. It can be found in many things, including paint, dust, soil, and water.

How does lead exposure happen?

Lead exposure can happen through many sources. Children may be exposed to lead by ingesting it (such as from lead-contaminated dust or soil), breathing it in (such as from old lead-based paint when it is disturbed during renovations), or through other means such as drinking contaminated water or eating food grown in contaminated soil.

How does lead affect the body?

Lead can interfere with the normal functioning of neurons and disrupt the formation of synapses. This can lead to cognitive and behavioral problems, including autism.

Can lead exposure be treated?

There is no cure for lead poisoning, but it can be managed. Treatment involves reducing exposure to lead and providing supportive care to manage symptoms.

How can I protect my child from lead exposure?

There are several steps you can take to protect your child from lead exposure:

  • Test your home for lead.
  • Use lead-free paint.
  • Avoid using traditional home remedies that may contain lead.
  • Wash hands and toys frequently.
  • Feed your child a healthy diet rich in calcium, iron, and vitamin C.

Is there a safe level of lead exposure?

No level of lead exposure is considered safe. Even low levels of exposure can have harmful effects on children's health and development.

Conclusion

Lead exposure and maternal fever during pregnancy are both potential risk factors for autism.

While more research is needed to fully understand the causes of autism, taking steps to prevent lead exposure and maternal fever can help reduce the risk.

If you are pregnant or planning to become pregnant, talk to your healthcare provider about ways to keep you and your baby healthy.